Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
Background: The residue-wise contact order (RWCO) describes the sequence separations between the residues of interest and its contacting residues in a protein sequence. It is a ne...
Misfolding of membrane proteins plays an important role in many human diseases such as retinitis pigmentosa, heredity deafness and diabetes insipidus. Single molecule force spectr...
Parameterized Appearance Models (PAMs) (e.g. eigentracking, active appearance models, morphable models) use Principal Component Analysis (PCA) to model the shape and appearance of...
Large-margin structured estimation methods minimize a convex upper bound of loss functions. While they allow for efficient optimization algorithms, these convex formulations are n...
Olivier Chapelle, Chuong B. Do, Quoc V. Le, Alexan...