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» A structural alignment kernel for protein structures
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BMCBI
2007
155views more  BMCBI 2007»
14 years 9 months ago
ProCMD: a database and 3D web resource for protein C mutants
Background: Activated Protein C (ProC) is an anticoagulant plasma serine protease which also plays an important role in controlling inflammation and cell proliferation. Several mu...
Pasqualina D'Ursi, Francesca Marino, Andrea Caprer...
IPPS
2005
IEEE
15 years 3 months ago
FROST: Revisited and Distributed
FROST (Fold Recognition-Oriented Search Tool) [6] is a software whose purpose is to assign a 3D structure to a protein sequence. It is based on a series of filters and uses a dat...
Vincent Poirriez, Rumen Andonov, Antoine Marin, Je...
CAIP
2009
Springer
155views Image Analysis» more  CAIP 2009»
15 years 4 months ago
Algorithms for the Sample Mean of Graphs
Measures of central tendency for graphs are important for protoype construction, frequent substructure mining, and multiple alignment of protein structures. This contribution propo...
Brijnesh J. Jain, Klaus Obermayer
92
Voted
BMCBI
2007
117views more  BMCBI 2007»
14 years 9 months ago
Supervised multivariate analysis of sequence groups to identify specificity determining residues
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
Iain M. Wallace, Desmond G. Higgins
87
Voted
GECCO
2004
Springer
137views Optimization» more  GECCO 2004»
15 years 3 months ago
Evolving Better Multiple Sequence Alignments
Aligning multiple DNA or protein sequences is a fundamental step in the analyses of phylogeny, homology and molecular structure. Heuristic algorithms are applied because optimal mu...
Luke Sheneman, James A. Foster