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» A structural alignment kernel for protein structures
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BMCBI
2002
133views more  BMCBI 2002»
14 years 9 months ago
Identification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model app
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
Kevin Truong, Mitsuhiko Ikura
BMCBI
2007
154views more  BMCBI 2007»
14 years 9 months ago
Inferring biological networks with output kernel trees
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
Pierre Geurts, Nizar Touleimat, Marie Dutreix, Flo...
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RECOMB
2006
Springer
15 years 10 months ago
Detecting the Dependent Evolution of Biosequences
Abstract. A probabilistic graphical model is developed in order to detect the dependent evolution between different sites in biological sequences. Given a multiple sequence alignme...
Jeremy Darot, Chen-Hsiang Yeang, David Haussler
KDD
2009
ACM
175views Data Mining» more  KDD 2009»
15 years 2 months ago
Multi-class protein fold recognition using large margin logic based divide and conquer learning
Inductive Logic Programming (ILP) systems have been successfully applied to solve complex problems in bioinformatics by viewing them as binary classification tasks. It remains an...
Huma Lodhi, Stephen Muggleton, Michael J. E. Stern...
BMCBI
2010
150views more  BMCBI 2010»
14 years 9 months ago
DeltaProt: a software toolbox for comparative genomics
Background: Statistical bioinformatics is the study of biological data sets obtained by new micro-technologies by means of proper statistical methods. For a better understanding o...
Steinar Thorvaldsen, Tor Flå, Nils Willassen