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» A structural alignment kernel for protein structures
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BMCBI
2005
100views more  BMCBI 2005»
14 years 9 months ago
EvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environments
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Jean-Christophe Gelly, Laurent Chiche, Jér&...
BMCBI
2008
149views more  BMCBI 2008»
14 years 9 months ago
Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Olivier Bastien, Eric Maréchal
NAR
2000
182views more  NAR 2000»
14 years 9 months ago
tmRDB (tmRNA database)
Maintained at the University of Texas Health Science Center at Tyler, Texas, the tmRNA database (tmRDB) is accessible at the URL http://psyche.uthct.edu/dbs/ tmRDB/tmRDB.html with...
Christian Zwieb, Jacek Wower
NAR
2000
117views more  NAR 2000»
14 years 9 months ago
The tmRNA Website
tmRNA (also known as 10Sa RNA) is so-named for its dual tRNA-like and mRNA-like nature. It is employed in a remarkable trans-translation process to add a Cterminal peptide tag to ...
Kelly P. Williams
ICASSP
2007
IEEE
15 years 3 months ago
Evolutionary Sequence Modeling for Discovery of Peptide Hormones
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...
M. Kemal Sönmez, Lawrence Toll, Nina Zaveri