77 search results - page 4 / 16 » A structural keystone for drug design |
100
click to vote
NAR
2006
14 years 11 months ago
2006
G-protein coupled receptors (GPCRs) represent one of the most important families of drug targets in pharmaceutical development. GPCR-LIgand DAtabase (GLIDA) is a novel public GPCR...
101
click to vote
BMCBI
2008
14 years 11 months ago
2008
Background: Target identification is important for modern drug discovery. With the advances in the development of molecular docking, potential binding proteins may be discovered b...
111
click to vote
BMCBI
2011
14 years 6 months ago
2011
Background: The amount of data on protein-protein interactions (PPIs) available in public databases and in the literature has rapidly expanded in recent years. PPI data can provid...
100
click to vote
CIBCB
2009
IEEE
15 years 24 days ago
2009
IEEE
Abstract-- The RNA secondary structure design (SSD) problem is a recently emerging research topic motivated by applications such as customized drug design and the self-assembly of ...
148
click to vote
CCE
2011
14 years 6 months ago
2011
The robustness of a system is a property that pervades all aspects of Nature. The ability of a system to adapt itself to perturbations due to internal and external agents, to agin...