77 search results - page 8 / 16 » A structural keystone for drug design |
109
click to vote
BIBM
2010
IEEE
14 years 9 months ago
2010
IEEE
ATP is a ubiquitous nucleotide that provides energy for cellular activities, catalyzes chemical reactions, and is involved in cellular signaling. The knowledge of the ATPprotein in...
GECCO
2005
Springer
15 years 5 months ago
2005
Springer
The prediction of the native structures of proteins, the socalled protein folding problem, is a NP hard multi-minima optimization problem for which to date no routine solutions ex...
101
click to vote
NAACL
2010
14 years 9 months ago
2010
Knowledge extraction from online repositories such as PubMed holds the promise of dramatically speeding up biomedical research and drug design. After initially focusing on recogni...
103
click to vote
BMCBI
2005
14 years 11 months ago
2005
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
BMCBI
2010
2010
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials
14 years 11 months ago
Background: Identification of novel drug targets and their inhibitors is a major challenge in the field of drug designing and development. Diaminopimelic acid (DAP) pathway is a u...