77 search results - page 9 / 16 » A structural keystone for drug design |
104
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COMPLIFE
2006
Springer
15 years 3 months ago
2006
Springer
A powerful new software concept to physiologically based pharmacokinetic (PBPK) modelling of drug disposition is presented. It links the inherent modular understanding in pharmacol...
105
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BMCBI
2010
14 years 11 months ago
2010
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
COCOON
2006
Springer
15 years 3 months ago
2006
Springer
: Inferring graphs from path frequency has been studied as an important problem which has a potential application to drug design and elucidation of chemical structures. Given a mul...
FPL
2008
Springer
15 years 1 months ago
2008
Springer
: Modeling the interactions of biological molecules, or docking is critical to both understanding basic life processes and to designing new drugs. Here we describe the FPGA-based a...
104
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RECOMB
2005
Springer
15 years 12 months ago
2005
Springer
We present a novel computational method, MultiBind, for recognition of binding patterns common to a set of protein structures. It is the first method which performs a multiple alig...