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» A survey of DNA motif finding algorithms
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BMCBI
2007
247views more  BMCBI 2007»
14 years 9 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai
BMCBI
2007
190views more  BMCBI 2007»
14 years 9 months ago
Discriminative motif discovery in DNA and protein sequences using the DEME algorithm
Background: Motif discovery aims to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to i...
Emma Redhead, Timothy L. Bailey
RECOMB
2005
Springer
15 years 10 months ago
Improved Pattern-Driven Algorithms for Motif Finding in DNA Sequences
Abstract. In order to guarantee that the optimal motif is found, traditional pattern-driven approaches perform an exhaustive search over all candidate motifs of length l. We develo...
Sing-Hoi Sze, Xiaoyan Zhao
RECOMB
2002
Springer
15 years 10 months ago
Finding motifs in the twilight zone
We introduce the notion of a multiprofile and use it for finding subtle motifs in DNA sequences. Multiprofiles generalize the notion of a profile and allow one to detect subtle co...
Uri Keich, Pavel A. Pevzner
APBC
2008
231views Bioinformatics» more  APBC 2008»
14 years 11 months ago
Optimal Algorithm for Finding DNA Motifs with Nucleotide Adjacent Dependency
: Finding motifs and the corresponding binding sites is a critical and challenging problem in studying the process of gene expression. String and matrix representations are two pop...
Francis Y. L. Chin, Henry C. M. Leung, Man-Hung Si...