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BMCBI
2008
133views more  BMCBI 2008»
14 years 10 months ago
MS-DOCK: Accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening
Background: The number of protein targets with a known or predicted tri-dimensional structure and of drug-like chemical compounds is growing rapidly and so is the need for new the...
Nicolas Sauton, David Lagorce, Bruno O. Villoutrei...
ICML
2004
IEEE
15 years 11 months ago
A graphical model for protein secondary structure prediction
In this paper, we present a graphical model for protein secondary structure prediction. This model extends segmental semi-Markov models (SSMM) to exploit multiple sequence alignme...
Wei Chu, Zoubin Ghahramani, David L. Wild
GECCO
2006
Springer
176views Optimization» more  GECCO 2006»
15 years 1 months ago
A genetic algorithm with backtracking for protein structure prediction
In this paper, we propose a simple genetic algorithm for finding the optimal conformation of a protein using the three-dimensional square HP model. A backtracking procedure is use...
Clayton Matthew Johnson, Anitha Katikireddy
ACL
1997
14 years 11 months ago
Learning Features that Predict Cue Usage
Our goal is to identify the features that predict the occurrence and placement of discourse cues in tutorial explanations in order to aid in the automatic generation of explanatio...
Barbara Di Eugenio, Johanna D. Moore, Massimo Paol...
GCB
1997
Springer
74views Biometrics» more  GCB 1997»
15 years 2 months ago
Using constraint programming for lattice protein folding
We present a global search technique for nding the global minimal conformation of a sequence in Dill's HP-lattice model5;6 . The HP-lattice model is a simpli ed model of prot...
Rolf Backofen