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BMCBI
2006
159views more  BMCBI 2006»
14 years 10 months ago
Prediction of protein continuum secondary structure with probabilistic models based on NMR solved structures
Background: The structure of proteins may change as a result of the inherent flexibility of some protein regions. We develop and explore probabilistic machine learning methods for...
Mikael Bodén, Zheng Yuan, Timothy L. Bailey
ISPD
1998
ACM
89views Hardware» more  ISPD 1998»
15 years 2 months ago
Timing metrics for physical design of deep submicron technologies
Performance-driven physical design is becoming more important as advances in IC technologies enable gigahertz operating frequencies. These same IC technologies, however, exhibit d...
Lawrence T. Pileggi
ACII
2007
Springer
15 years 4 months ago
Early Prediction of Student Frustration
Affective reasoning has been the subject of increasing attention in recent years. Because negative affective states such as frustration and anxiety can impede progress toward learn...
Scott W. McQuiggan, Sunyoung Lee, James C. Lester
BMCBI
2007
143views more  BMCBI 2007»
14 years 10 months ago
An adaptive bin framework search method for a beta-sheet protein homopolymer model
Background: The problem of protein structure prediction consists of predicting the functional or native structure of a protein given its linear sequence of amino acids. This probl...
Alena Shmygelska, Holger H. Hoos
CSB
2005
IEEE
124views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Multi-Scale Hierarchical Structure Prediction of Helical Transmembrane Proteins
As the first step toward a multi-scale, hierarchical computational approach for membrane protein structure prediction, the packing of transmembrane helices was modeled at the resi...
Zhong Chen, Ying Xu