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» AS Relationships: Inference and Validation
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BMCBI
2006
122views more  BMCBI 2006»
14 years 9 months ago
A multivariate prediction model for microarray cross-hybridization
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
Yian A. Chen, Cheng-Chung Chou, Xinghua Lu, Elizab...
BMCBI
2006
89views more  BMCBI 2006»
14 years 9 months ago
A joint model for nonparametric functional mapping of longitudinal trajectory and time-to-event
Background: The characterization of the relationship between a longitudinal response process and a time-to-event has been a pressing challenge in biostatistical research. This has...
Min Lin, Rongling Wu
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BMCBI
2006
233views more  BMCBI 2006»
14 years 9 months ago
AbMiner: A bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic,
Background: Monoclonal antibodies are used extensively throughout the biomedical sciences for detection of antigens, either in vitro or in vivo. We, for example, have used them fo...
Sylvia M. Major, Satoshi Nishizuka, Daisaku Morita...
BMCBI
2007
78views more  BMCBI 2007»
14 years 9 months ago
Improved human disease candidate gene prioritization using mouse phenotype
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
Jing Chen, Huan Xu, Bruce J. Aronow, Anil G. Jegga
JCB
2008
90views more  JCB 2008»
14 years 9 months ago
A Simple Model of the Modular Structure of Transcriptional Regulation in Yeast
Resolving the general organizational principles that govern the interactions during transcriptional gene regulation has great relevance for understanding disease progression, biof...
Vladimir Filkov, Nameeta Shah