Sciweavers

1266 search results - page 52 / 254
» AS Relationships: Inference and Validation
Sort
View
BMCBI
2010
160views more  BMCBI 2010»
14 years 10 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
BMCBI
2010
150views more  BMCBI 2010»
14 years 10 months ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
BMCBI
2007
174views more  BMCBI 2007»
14 years 10 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li
BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
14 years 9 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
JMLR
2010
165views more  JMLR 2010»
14 years 4 months ago
Causal Inference
: This review presents empirical researchers with recent advances in causal inference, and stresses the paradigmatic shifts that must be undertaken in moving from traditional stati...
Judea Pearl