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» AS Relationships: Inference and Validation
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JCB
2007
130views more  JCB 2007»
14 years 9 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
RECOMB
2005
Springer
15 years 10 months ago
Causal Inference of Regulator-Target Pairs by Gene Mapping of Expression Phenotypes
Background: Correlations between polymorphic markers and observed phenotypes provide the basis for mapping traits in quantitative genetics. When the phenotype is gene expression, ...
David Kulp, Manjunatha Jagalur
BMCBI
2010
100views more  BMCBI 2010»
14 years 10 months ago
Scaffold filling, contig fusion and comparative gene order inference
Background: There has been a trend in increasing the phylogenetic scope of genome sequencing without finishing the sequence of the genome. Increasing numbers of genomes are being ...
Adriana Muñoz, Chunfang Zheng, Qian Zhu, Vi...
ISI
2006
Springer
14 years 9 months ago
Entity Workspace: An Evidence File That Aids Memory, Inference, and Reading
An intelligence analyst often needs to keep track of more facts than can be held in human memory. As a result, analysts use a notebook or evidence file to record facts learned so f...
Eric A. Bier, Edward W. Ishak, Ed Chi
INFORMS
1998
150views more  INFORMS 1998»
14 years 9 months ago
Branch and Infer: A Unifying Framework for Integer and Finite Domain Constraint Programming
constraint abstractions into integer programming, and to discuss possible combinations of the two approaches. Combinatorial problems are ubiquitous in many real world applications ...
Alexander Bockmayr, Thomas Kasper