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CORR
2010
Springer
117views Education» more  CORR 2010»
15 years 4 months ago
Reductions Between Expansion Problems
The Small-Set Expansion Hypothesis (Raghavendra, Steurer, STOC 2010) is a natural hardness assumption concerning the problem of approximating the edge expansion of small sets in g...
Prasad Raghavendra, David Steurer, Madhur Tulsiani
BMCBI
2006
143views more  BMCBI 2006»
15 years 4 months ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
JCB
2008
90views more  JCB 2008»
15 years 4 months ago
A Simple Model of the Modular Structure of Transcriptional Regulation in Yeast
Resolving the general organizational principles that govern the interactions during transcriptional gene regulation has great relevance for understanding disease progression, biof...
Vladimir Filkov, Nameeta Shah
BMCBI
2005
106views more  BMCBI 2005»
15 years 3 months ago
A multistep bioinformatic approach detects putative regulatory elements in gene promoters
Background: Searching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge ...
Stefania Bortoluzzi, Alessandro Coppe, Andrea Biso...
BMCBI
2005
122views more  BMCBI 2005»
15 years 3 months ago
Quantitative analysis of EGR proteins binding to DNA: assessing additivity in both the binding site and the protein
Background: Recognition codes for protein-DNA interactions typically assume that the interacting positions contribute additively to the binding energy. While this is known to not ...
Jiajian Liu, Gary D. Stormo