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BMCBI
2010
105views more  BMCBI 2010»
15 years 1 months ago
Subdivision of the MDR superfamily of medium-chain dehydrogenases/reductases through iterative hidden Markov model refinement
Background: The Medium-chain Dehydrogenases/Reductases (MDR) form a protein superfamily whose size and complexity defeats traditional means of subclassification; it currently has ...
Joel Hedlund, Hans Jörnvall, Bengt Persson
ISMB
2000
15 years 3 months ago
Prediction of the Number of Residue Contacts in Proteins
Knowing the number of residue contacts in a protein is crucial for deriving constraints useful in modeling protein folding, protein structure, and/or scoring remote homology searc...
Piero Fariselli, Rita Casadio
BMCBI
2007
155views more  BMCBI 2007»
15 years 1 months ago
ProCMD: a database and 3D web resource for protein C mutants
Background: Activated Protein C (ProC) is an anticoagulant plasma serine protease which also plays an important role in controlling inflammation and cell proliferation. Several mu...
Pasqualina D'Ursi, Francesca Marino, Andrea Caprer...
RECOMB
2003
Springer
16 years 1 months ago
A multi-expert system for the automatic detection of protein domains from sequence information
We describe a novel method for detecting the domain structure of a protein from sequence information alone. The method is based on analyzing multiple sequence alignments that are ...
Niranjan Nagarajan, Golan Yona
NAR
2011
227views Computer Vision» more  NAR 2011»
14 years 8 months ago
VnD: a structure-centric database of disease-related SNPs and drugs
Numerous genetic variations have been found to be related to human diseases. Significant portion of those affect the drug response as well by changing the protein structure and fu...
Jin Ok Yang, Sangho Oh, Gunhwan Ko, Seong-Jin Park...