Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
Many basic tasks in computational biology involve operations on individual DNA and protein sequences. These sequences, even when anonymized, are vulnerable to re-identification a...
Background: Bioinformatics tools are commonly used for assessing potential protein allergenicity. While these methods have achieved good accuracies for highly conserved sequences,...
Shen Jean Lim, Joo Chuan Tong, Fook Tim Chew, Mart...
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...