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BMCBI
2011
14 years 8 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
PET
2009
Springer
15 years 8 months ago
Vida: How to Use Bayesian Inference to De-anonymize Persistent Communications
We present the Vida family of abstractions of anonymous communication systems, model them probabilistically and apply Bayesian inference to extract patterns of communications and u...
George Danezis, Carmela Troncoso
BMCBI
2006
180views more  BMCBI 2006»
15 years 1 months ago
Building multiclass classifiers for remote homology detection and fold recognition
Motivation Protein remote homology prediction and fold recognition are central problems in computational biology. Supervised learning algorithms based on support vector machines a...
Huzefa Rangwala, George Karypis
100
Voted
BMCBI
2010
119views more  BMCBI 2010»
15 years 1 months ago
Coherent pipeline for biomarker discovery using mass spectrometry and bioinformatics
Background: Robust biomarkers are needed to improve microbial identification and diagnostics. Proteomics methods based on mass spectrometry can be used for the discovery of novel ...
Ali Al-Shahib, Raju Misra, Nadia Ahmod, Min Fang, ...
122
Voted
BMCBI
2006
92views more  BMCBI 2006»
15 years 1 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...