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BIBE
2007
IEEE
129views Bioinformatics» more  BIBE 2007»
15 years 5 months ago
Statistial Analysis of nucleosome occupancy and histone modification data
Abstract-- In eukaryotic cells, genomic DNAs wrap around beadlike molecules, called nucleosomes, so as to pack more compactly in the nucleus of the cell. The nucleosome is made up ...
Guo-Cheng Yuan, Jun S. Liu
BMCBI
2006
84views more  BMCBI 2006»
15 years 1 months ago
Inferring topology from clustering coefficients in protein-protein interaction networks
Background: Although protein-protein interaction networks determined with high-throughput methods are incomplete, they are commonly used to infer the topology of the complete inte...
Caroline C. Friedel, Ralf Zimmer
BMCBI
2005
153views more  BMCBI 2005»
15 years 1 months ago
Mining published lists of cancer related microarray experiments: Identification of a gene expression signature having a critical
Background: Routine application of gene expression microarray technology is rapidly producing large amounts of data that necessitate new approaches of analysis. The analysis of a ...
Giacomo Finocchiaro, Francesco Mancuso, Heiko M&uu...
EVOW
2009
Springer
15 years 8 months ago
Validation of a Morphogenesis Model of Drosophila Early Development by a Multi-objective Evolutionary Optimization Algorithm
We apply evolutionary computation to calibrate the parameters of a morphogenesis model of Drosophila early development. The model aims to describe the establishment of the steady g...
Rui Dilão, Daniele Muraro, Miguel Nicolau, ...
BIB
2006
84views more  BIB 2006»
15 years 1 months ago
Computational methodologies for modelling, analysis and simulation of signalling networks
This article is a critical review of computational techniques used to model, analyse and simulate signalling networks. We propose a conceptual framework, and discuss the role of s...
David R. Gilbert, Hendrik Fuß, Xu Gu, Richar...