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CANDC
2007
ACM
15 years 1 months ago
Chromosome segregation in Escherichia coli division: A free energy-driven string model
Although the mechanisms of eukaryotic chromosome segregation and cell division have been elucidated to a certain extent, those for bacteria remain largely unknown. Here we present...
Jianmiao Fan, Kagan Tuncay, Peter J. Ortoleva
126
Voted
JCB
2002
131views more  JCB 2002»
15 years 1 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
LION
2009
Springer
114views Optimization» more  LION 2009»
15 years 8 months ago
Substitution Matrices and Mutual Information Approaches to Modeling Evolution
Abstract. Substitution matrices are at the heart of Bioinformatics: sequence alignment, database search, phylogenetic inference, protein family classication are based on Blosum, P...
Stephan Kitchovitch, Yuedong Song, Richard C. van ...
BMCBI
2008
103views more  BMCBI 2008»
15 years 1 months ago
Parameter estimation for robust HMM analysis of ChIP-chip data
Background: Tiling arrays are an important tool for the study of transcriptional activity, proteinDNA interactions and chromatin structure on a genome-wide scale at high resolutio...
Peter Humburg, David Bulger, Glenn Stone
127
Voted
PDPTA
2008
15 years 3 months ago
Predicting Web Cache Behavior using Stochastic State-Space Models
Web caches play an important role in improving the surfing experience of Web clients and reducing the network traffic seen by Web servers. Accurate analytical models of Web caches ...
Amitayu Das, Ritendra Datta, Bhuvan Urgaonkar, Ana...