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DILS
2004
Springer
15 years 6 months ago
Links and Paths through Life Sciences Data Sources
An abundance of biological data sources contain data on classes of scientific entities, such as genes and sequences. Logical relationships between scientific objects are implemen...
Zoé Lacroix, Hyma Murthy, Felix Naumann, Lo...
ECAL
2007
Springer
15 years 7 months ago
Folding Protein-Like Structures with Open L-Systems
Abstract. Proteins, under native conditions, fold to specific 3D structures according to their 1D amino acid sequence, which in turn is defined by the genetic code. The specific...
Gemma B. Danks, Susan Stepney, Leo S. D. Caves
NAR
2007
136views more  NAR 2007»
15 years 28 days ago
DBAli tools: mining the protein structure space
The DBAli tools use a comprehensive set of structural alignments in the DBAli database to leverage the structural information deposited in the Protein Data Bank (PDB). These tools...
Marc A. Martí-Renom, Ursula Pieper, Mallur ...
BMCBI
2010
123views more  BMCBI 2010»
14 years 8 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke
BMCBI
2005
106views more  BMCBI 2005»
15 years 1 months ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...