An abundance of biological data sources contain data on classes of scientific entities, such as genes and sequences. Logical relationships between scientific objects are implemen...
Abstract. Proteins, under native conditions, fold to specific 3D structures according to their 1D amino acid sequence, which in turn is defined by the genetic code. The specific...
The DBAli tools use a comprehensive set of structural alignments in the DBAli database to leverage the structural information deposited in the Protein Data Bank (PDB). These tools...
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...