Background: Intrinsically disordered proteins play important roles in various cellular activities and their prevalence was implicated in a number of human diseases. The knowledge ...
Marcin J. Mizianty, Tuo Zhang, Bin Xue, Yaoqi Zhou...
Abstract. It is estimated that 20% of genes in the human genome encode for integral membrane proteins (IMPs) and some estimates are much higher. IMPs control a broad range of event...
There are several dimensions and levels of complexity in which information on protein motifs may be available. For example, onedimensional sequence motifs may be associated with s...
Darrell Conklin, Suzanne Fortier, Janice I. Glasgo...
Abstract. Current approaches for identification and detection of transcription factor binding sites rely on an extensive set of known target genes. Here we describe a novel structu...
Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...