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RECOMB
2004
Springer
16 years 1 months ago
Discovering temporal relations in molecular pathways using protein-protein interactions
The availability of large-scale protein-protein interaction data provides us with many opportunities to study molecular pathways involving proteins. In this paper we propose to mi...
Martin Farach-Colton, Yang Huang, John L. L. Woolf...
BMCBI
2006
127views more  BMCBI 2006»
15 years 1 months ago
Automatic discovery of cross-family sequence features associated with protein function
Background: Methods for predicting protein function directly from amino acid sequences are useful tools in the study of uncharacterised protein families and in comparative genomic...
Markus Brameier, Josien Haan, Andrea Krings, Rober...
BMCBI
2007
96views more  BMCBI 2007»
15 years 1 months ago
Structure and function predictions of the Msa protein in Staphylococcus aureus
Background: Staphylococcus aureus is a human pathogen that causes a wide variety of lifethreatening infections using a large number of virulence factors. One of the major global r...
Vijayaraj Nagarajan, Mohamed O. Elasri
GECCO
2006
Springer
133views Optimization» more  GECCO 2006»
15 years 5 months ago
String transformation-based Bayesian classification or proteins
We describe a Markov chain Bayesian classification tool, SCS, that can perform data-driven classification of proteins and protein segments. Training data for interesting classific...
Timothy Meekhof, Gary W. Daughdrill, Robert B. Hec...
BMCBI
2010
101views more  BMCBI 2010»
15 years 1 months ago
Hidden Markov model speed heuristic and iterative HMM search procedure
Background: Profile hidden Markov models (profile-HMMs) are sensitive tools for remote protein homology detection, but the main scoring algorithms, Viterbi or Forward, require con...
L. Steven Johnson, Sean R. Eddy, Elon Portugaly