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126
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RECOMB
2003
Springer
16 years 1 months ago
Accurate detection of very sparse sequence motifs
Protein sequence alignments are more reliable the shorter the evolutionary distance. Here, we align distantly related proteins using many closely spaced intermediate sequences as ...
Andreas Heger, Michael Lappe, Liisa Holm
BMCBI
2006
144views more  BMCBI 2006»
15 years 1 months ago
Association algorithm to mine the rules that govern enzyme definition and to classify protein sequences
Background: The number of sequences compiled in many genome projects is growing exponentially, but most of them have not been characterized experimentally. An automatic annotation...
Shih-Hau Chiu, Chien-Chi Chen, Gwo-Fang Yuan, Thy-...
GECCO
2006
Springer
176views Optimization» more  GECCO 2006»
15 years 5 months ago
A genetic algorithm with backtracking for protein structure prediction
In this paper, we propose a simple genetic algorithm for finding the optimal conformation of a protein using the three-dimensional square HP model. A backtracking procedure is use...
Clayton Matthew Johnson, Anitha Katikireddy
RECOMB
2009
Springer
16 years 2 months ago
Searching Protein 3-D Structures in Linear Time
Finding similar structures from 3-D structure databases of proteins is becoming more and more important issue in the post-genomic molecular biology. To compare 3-D structures of tw...
Tetsuo Shibuya
120
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ENTCS
2010
118views more  ENTCS 2010»
14 years 11 months ago
Fragments-based Model Reduction: Some Case Studies
Molecular biological models usually suffer from a dramatic combinatorial blow up. Indeed, proteins form complexes and can modify each others, which leads to the formation of a hug...
Jérôme Feret