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132
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BMCBI
2008
15 years 3 months ago
2008
Background: We propose a statistically principled baseline correction method, derived from a parametric smoothing model. It uses a score function to describe the key features of b...
127
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
113
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BMCBI
2010
15 years 3 months ago
2010
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
133
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BMCBI
2010
15 years 3 months ago
2010
Background: Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment. While these lists represent an accurat...
138
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: The existence of negative correlations between degrees of interacting proteins is being discussed since such negative degree correlations were found for the large-scal...