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CSB
2003
IEEE
106views Bioinformatics» more  CSB 2003»
15 years 7 months ago
Reconstruction of Ancestral Gene Order after Segmental Duplication and Gene Loss
As gene order evolves through a variety of chromosomal rearrangements, conserved segments provide important insight into evolutionary relationships and functional roles of genes. ...
Jun Huan, Jan Prins, Wei Wang 0010, Todd J. Vision
123
Voted
ISMB
1998
15 years 3 months ago
A Hidden Markov Model for Predicting Transmembrane Helices in Protein Sequences
A novel method to model and predict the location and orientation of alpha helices in membrane- spanning proteins is presented. It is based on a hidden Markov model (HMM) with an a...
Erik L. L. Sonnhammer, Gunnar von Heijne, Anders K...
JCB
2006
123views more  JCB 2006»
15 years 1 months ago
Reconstructing Ancestral Haplotypes with a Dictionary Model
We propose a dictionary model for haplotypes. According to the model, a haplotype is constructed by randomly concatenating haplotype segments from a given dictionary of segments. ...
Kristin L. Ayers, Chiara Sabatti, Kenneth Lange
97
Voted
BMCBI
2010
89views more  BMCBI 2010»
15 years 1 months ago
Detection of gene pathways with predictive power for breast cancer prognosis
Background: Prognosis is of critical interest in breast cancer research. Biomedical studies suggest that genomic measurements may have independent predictive power for prognosis. ...
Shuangge Ma, Michael R. Kosorok
BMCBI
2008
193views more  BMCBI 2008»
15 years 1 months ago
Missing value imputation for microarray gene expression data using histone acetylation information
Background: It is an important pre-processing step to accurately estimate missing values in microarray data, because complete datasets are required in numerous expression profile ...
Qian Xiang, Xianhua Dai, Yangyang Deng, Caisheng H...