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    BMCBI
    2006
    130views more  BMCBI 2006»
    An accurate and interpretable model for siRNA efficacy prediction
    13 years 6 months ago
    An accurate and interpretable model for siRNA efficacy prediction
    Download  www.biomedcentral.com
    Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
    Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
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    BMCBI
    2004
    177views more  BMCBI 2004»
    Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
    13 years 6 months ago
    Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
    Download  www.biomedcentral.com
    Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
    Andrew F. Neuwald, Jun S. Liu
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    HICSS
    1994
    IEEE
    157views Biometrics» more  HICSS 1994»
    A Protein Family Classification Method for Analysis of Large DNA Sequences
    13 years 10 months ago
    A Protein Family Classification Method for Analysis of Large DNA Sequences
    Download  bioinformatics.weizmann.ac.il
    A method is described for identification and classification of proteins encoded in large DNA sequences. Previously, an automated system was introduced for the general detection of...
    Steven Henikoff, Jorja G. Henikoff
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    RECOMB
    2008
    Springer
    107views Computational Biology» more  RECOMB 2008»
    Integrating Sequence and Topology for Efficient and Accurate Detection of Horizontal Gene Transfer
    14 years 6 months ago
    Integrating Sequence and Topology for Efficient and Accurate Detection of Horizontal Gene Transfer
    Download  www.cs.rice.edu
    Abstract. One phylogeny-based approach to horizontal gene transfer (HGT) detection entails comparing the topology of a gene tree to that of the species tree, and using their differ...
    Cuong Than, Guohua Jin, Luay Nakhleh
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    RECOMB
    2005
    Springer
    76views Computational Biology» more  RECOMB 2005»
    Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
    14 years 6 months ago
    Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
    Download  cbio.uct.ac.za
    Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
    Cathal Seoighe, Konrad Scheffler
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