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BMCBI
2008
100views more  BMCBI 2008»
14 years 9 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
COMCOM
2006
119views more  COMCOM 2006»
14 years 9 months ago
From content distribution networks to content networks - issues and challenges
Due to the technical developments in electronics the amount of digital content is continuously increasing. In order to make digital content respectively multimedia content availab...
Thomas Plagemann, Vera Goebel, Andreas Mauthe, Lau...
JSW
2008
202views more  JSW 2008»
14 years 9 months ago
Change Prediction in Object-Oriented Software Systems: A Probabilistic Approach
An estimation of change-proneness of parts of a software system is an active topic in the area of software engineering. Such estimates can be used to predict changes to different c...
Ali R. Sharafat, Ladan Tahvildari
SIGMOD
2008
ACM
138views Database» more  SIGMOD 2008»
14 years 9 months ago
Configuration-parametric query optimization for physical design tuning
Automated physical design tuning for database systems has recently become an active area of research and development. Existing tuning tools explore the space of feasible solutions...
Nicolas Bruno, Rimma V. Nehme
BMCBI
2005
114views more  BMCBI 2005»
14 years 9 months ago
Systematic analysis of human kinase genes: a large number of genes and alternative splicing events result in functional and stru
Background: Protein kinases are a well defined family of proteins, characterized by the presence of a common kinase catalytic domain and playing a significant role in many importa...
Luciano Milanesi, Mauro Petrillo, Leandra Sepe, An...