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BMCBI
2010
131views more  BMCBI 2010»
15 years 6 months ago
A comparison of approximation techniques for variance-based sensitivity analysis of biochemical reaction systems
Background: Sensitivity analysis is an indispensable tool for the analysis of complex systems. In a recent paper, we have introduced a thermodynamically consistent variance-based ...
Hong-Xuan Zhang, John Goutsias
BMCBI
2007
186views more  BMCBI 2007»
15 years 6 months ago
GeneBins: a database for classifying gene expression data, with application to plant genome arrays
Background: To interpret microarray experiments, several ontological analysis tools have been developed. However, current tools are limited to specific organisms. Results: We deve...
Nicolas Goffard, Georg Weiller
BMCBI
2007
103views more  BMCBI 2007»
15 years 6 months ago
Dynamic simulation of regulatory networks using SQUAD
Background: The ambition of most molecular biologists is the understanding of the intricate network of molecular interactions that control biological systems. As scientists uncove...
Alessandro Di Cara, Abhishek Garg, Giovanni De Mic...
BMCBI
2008
97views more  BMCBI 2008»
15 years 6 months ago
SiteSeek: Post-translational modification analysis using adaptive locality-effective kernel methods and new profiles
Background: Post-translational modifications have a substantial influence on the structure and functions of protein. Post-translational phosphorylation is one of the most common m...
Paul D. Yoo, Yung Shwen Ho, Bing Bing Zhou, Albert...
BMCBI
2008
118views more  BMCBI 2008»
15 years 6 months ago
Drug interaction prediction using ontology-driven hypothetical assertion framework for pathway generation followed by numerical
Background: In accordance with the increasing amount of information concerning individual differences in drug response and molecular interaction, the role of in silico prediction ...
Takeshi Arikuma, Sumi Yoshikawa, Ryuzo Azuma, Kent...
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