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BMCBI
2008
130views more  BMCBI 2008»
14 years 10 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2006
92views more  BMCBI 2006»
14 years 10 months ago
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
Bradford C. Powell, Clyde A. Hutchison III
VLC
2010
91views more  VLC 2010»
14 years 8 months ago
A model-based recognition engine for sketched diagrams
Many of today’s recognition approaches for hand-drawn sketches are feature-based, which is conceptually similar to the recognition of hand-written text. While very suitable for ...
Florian Brieler, Mark Minas
EDBT
2011
ACM
256views Database» more  EDBT 2011»
14 years 1 months ago
RanKloud: a scalable ranked query processing framework on hadoop
The popularity of batch-oriented cluster architectures like Hadoop is on the rise. These batch-based systems successfully achieve high degrees of scalability by carefully allocati...
K. Selçuk Candan, Parth Nagarkar, Mithila N...
SIGMOD
2004
ACM
262views Database» more  SIGMOD 2004»
15 years 10 months ago
The Next Database Revolution
Database system architectures are undergoing revolutionary changes. Most importantly, algorithms and data are being unified by integrating programming languages with the database ...
Jim Gray