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152
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BIOINFORMATICS
2007
15 years 4 months ago
2007
Motivation: Protein–protein complexes are known to play key roles in many cellular processes. However, they are often not accessible to experimental study because of their low s...
176
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BIOINFORMATICS
2008
15 years 4 months ago
2008
Motivation: Finding a good network null model for protein-protein interaction (PPI) networks is a fundamental issue. Such a model would provide insights into the interplay between...
137
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BMCBI
2010
15 years 4 months ago
2010
Background: Typically, pooling of mRNA samples in microarray experiments implies mixing mRNA from several biological-replicate samples before hybridization onto a microarray chip....
125
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BMCBI
2010
15 years 4 months ago
2010
Background: It has been long well known that genes do not act alone; rather groups of genes act in consort during a biological process. Consequently, the expression levels of gene...
145
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BMCBI
2010
15 years 4 months ago
2010
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...