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130
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BMCBI
2007
15 years 4 months ago
2007
Background: Identity by descent (IBD) matrix estimation is a central component in mapping of Quantitative Trait Loci (QTL) using variance component models. A large number of algor...
132
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BMCBI
2007
15 years 4 months ago
2007
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
143
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BMCBI
2007
15 years 4 months ago
2007
Background: Biological sequence repeats arranged in tandem patterns are widespread in DNA and proteins. While many software tools have been designed to detect DNA tandem repeats (...
107
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BMCBI
2007
15 years 4 months ago
2007
Background: DNA melting curve analysis using double-stranded DNA-specific dyes such as SYTO9 produce complex and reproducible melting profiles, resulting in the detection of multi...
127
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BMCBI
2008
15 years 4 months ago
2008
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...