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113
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BMCBI
2006
81views more  BMCBI 2006»
15 years 3 months ago
Multipolar representation of protein structure
Background: That the structure determines the function of proteins is a central paradigm in biology. However, protein functions are more directly related to cooperative effects at...
Apostol Gramada, Philip E. Bourne
133
Voted
BMCBI
2006
124views more  BMCBI 2006»
15 years 3 months ago
ZCURVE_V: a new self-training system for recognizing protein-coding genes in viral and phage genomes
Background: It necessary to use highly accurate and statistics-based systems for viral and phage genome annotations. The GeneMark systems for gene-finding in virus and phage genom...
Feng-Biao Guo, Chun-Ting Zhang
141
Voted
BMCBI
2006
145views more  BMCBI 2006»
15 years 3 months ago
Fast-Find: A novel computational approach to analyzing combinatorial motifs
Background: Many vital biological processes, including transcription and splicing, require a combination of short, degenerate sequence patterns, or motifs, adjacent to defined seq...
Micah Hamady, Erin Peden, Rob Knight, Ravinder Sin...
136
Voted
BMCBI
2006
135views more  BMCBI 2006»
15 years 3 months ago
TF Target Mapper: A BLAST search tool for the identification of Transcription Factor target genes
Background: In the current era of high throughput genomics a major challenge is the genome-wide identification of target genes for specific transcription factors. Chromatin immuno...
Sebastiaan Horsman, Michael J. Moorhouse, Victor C...
156
Voted
BMCBI
2006
174views more  BMCBI 2006»
15 years 3 months ago
CARAT: A novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...
Jing Huang, Wen Wei, Joyce Chen, Jane Zhang, Guoyi...
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