Background: Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. These recombination events can be obscured by subsequent resid...
Background: Cellular metabolism can be characterized by networks of enzymatic reactions and transport processes capable of supporting cellular life. Our aim is to find evolutionar...
Hee Shin Kim, Jay E. Mittenthal, Gustavo Caetano-A...
Background: The development and testing of functions for the modeling of protein energetics is an important part of current research aimed at understanding protein structure and f...
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Background: The subcellular location of a protein is closely related to its function. It would be worthwhile to develop a method to predict the subcellular location for a given pr...