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148
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BMCBI
2005
15 years 3 months ago
2005
Background: Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profi...
126
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BMCBI
2005
15 years 3 months ago
2005
Background: Translational research requires taking basic science observations and developing them into clinically useful tests and therapeutics. We have developed a process to dev...
165
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BMCBI
2005
15 years 3 months ago
2005
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
250
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BMCBI
2005
15 years 3 months ago
2005
Background: Alignment of RNA secondary structures is important in studying functional RNA motifs. In recent years, much progress has been made in RNA motif finding and structure a...
119
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BMCBI
2005
15 years 3 months ago
2005
Background: Generalized hidden Markov models (GHMMs) appear to be approaching acceptance as a de facto standard for state-of-the-art ab initio gene finding, as evidenced by the re...