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ROCAI
2004
Springer
15 years 6 months ago
Learning Mixtures of Localized Rules by Maximizing the Area Under the ROC Curve
We introduce a model class for statistical learning which is based on mixtures of propositional rules. In our mixture model, the weight of a rule is not uniform over the entire ins...
Tobias Sing, Niko Beerenwinkel, Thomas Lengauer
CSB
2004
IEEE
177views Bioinformatics» more  CSB 2004»
15 years 4 months ago
High-Throughput 3D Structural Homology Detection via NMR Resonance Assignment
One goal of the structural genomics initiative is the identification of new protein folds. Sequence-based structural homology prediction methods are an important means for priorit...
Christopher James Langmead, Bruce Randall Donald
92
Voted
ALMOB
2008
95views more  ALMOB 2008»
15 years 1 months ago
A stitch in time: Efficient computation of genomic DNA melting bubbles
Background: It is of biological interest to make genome-wide predictions of the locations of DNA melting bubbles using statistical mechanics models. Computationally, this poses th...
Eivind Tøstesen
91
Voted
BMCBI
2010
103views more  BMCBI 2010»
15 years 1 months ago
Nonparametric methods for the analysis of single-color pathogen microarrays
Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, an...
Omar J. Jabado, Sean Conlan, P. Lan Quan, Jeffrey ...
BMCBI
2008
136views more  BMCBI 2008»
15 years 1 months ago
LOMA: A fast method to generate efficient tagged-random primers despite amplification bias of random PCR on pathogens
Background: Pathogen detection using DNA microarrays has the potential to become a fast and comprehensive diagnostics tool. However, since pathogen detection chips currently utili...
Wah-Heng Lee, Christopher W. Wong, Wan Yee Leong, ...