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BMCBI
2004
125views more  BMCBI 2004»
14 years 11 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...
NAR
2011
223views Computer Vision» more  NAR 2011»
14 years 2 months ago
HitPredict: a database of quality assessed protein-protein interactions in nine species
Despite the availability of a large number of protein– protein interactions (PPIs) in several species, researchers are often limited to using very small subsets in a few organis...
Ashwini Patil, Kenta Nakai, Haruki Nakamura
ISMB
1994
15 years 1 months ago
Predicting Location and Structure Of beta-Sheet Regions Using Stochastic Tree Grammars
We describe and demonstrate the effectiveness of a method of predicting protein secondary structures, sheet regions in particular, using a class of stochastic tree grammars as rep...
Hiroshi Mamitsuka, Naoki Abe
BMCBI
2004
150views more  BMCBI 2004»
14 years 11 months ago
Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs
Background: The wealth of information on protein structure has led to a variety of statistical analyses of the role played by individual amino acid types in the protein fold. In p...
Gareth Williams, Patrick Doherty
BMCBI
2007
141views more  BMCBI 2007»
14 years 12 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...