Determining the number and location of disulfide bonds within a protein provide valuable insight into the protein’s three-dimensional structure. Purely computational methods tha...
Timothy Lee, Rahul Singh, Ten-Yang Yen, Bruce Mach...
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
Background: Protein kinases are a well defined family of proteins, characterized by the presence of a common kinase catalytic domain and playing a significant role in many importa...
A function of a protein is dependent on its structure; therefore, predicting a protein structure from an amino acid sequence is an active area of research. Optimally predicting a ...
Background: Structure prediction of membrane proteins is still a challenging computational problem. Hidden Markov models (HMM) have been successfully applied to the problem of pre...
Piero Fariselli, Pier Luigi Martelli, Rita Casadio