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» Agent-based protein structure prediction
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CBMS
2006
IEEE
15 years 5 months ago
MS2DB: An Algorithmic Approach to Determine Disulfide Linkage Patterns
Determining the number and location of disulfide bonds within a protein provide valuable insight into the protein’s three-dimensional structure. Purely computational methods tha...
Timothy Lee, Rahul Singh, Ten-Yang Yen, Bruce Mach...
BMCBI
2007
97views more  BMCBI 2007»
14 years 12 months ago
Relating destabilizing regions to known functional sites in proteins
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
BMCBI
2005
114views more  BMCBI 2005»
14 years 11 months ago
Systematic analysis of human kinase genes: a large number of genes and alternative splicing events result in functional and stru
Background: Protein kinases are a well defined family of proteins, characterized by the presence of a common kinase catalytic domain and playing a significant role in many importa...
Luciano Milanesi, Mauro Petrillo, Leandra Sepe, An...
IJBRA
2007
80views more  IJBRA 2007»
14 years 11 months ago
On predicting secondary structure transition
A function of a protein is dependent on its structure; therefore, predicting a protein structure from an amino acid sequence is an active area of research. Optimally predicting a ...
Raja Loganantharaj, Vivek Philip
BMCBI
2005
114views more  BMCBI 2005»
14 years 11 months ago
A new decoding algorithm for hidden Markov models improves the prediction of the topology of all-beta membrane proteins
Background: Structure prediction of membrane proteins is still a challenging computational problem. Hidden Markov models (HMM) have been successfully applied to the problem of pre...
Piero Fariselli, Pier Luigi Martelli, Rita Casadio