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» Agent-based protein structure prediction
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BMCBI
2011
14 years 6 months ago
A quality metric for homology modeling: the H-factor
Background: The analysis of protein structures provides fundamental insight into most biochemical functions and consequently into the cause and possible treatment of diseases. As ...
Eric di Luccio, Patrice Koehl
BMCBI
2008
145views more  BMCBI 2008»
14 years 12 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
ISMB
1996
15 years 1 months ago
Refining Neural Network Predictions for Helical Transmembrane Proteins by Dynamic Programming
For transmembrane proteins experimental determina-tion of three-dimensional structure is problematic. However, membrane proteins have important impact for molecular biology in gen...
Burkhard Rost, Rita Casadio, Piero Fariselli
BMCBI
2008
228views more  BMCBI 2008»
14 years 12 months ago
Adaptive diffusion kernel learning from biological networks for protein function prediction
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...
Liang Sun, Shuiwang Ji, Jieping Ye
BMCBI
2010
127views more  BMCBI 2010»
14 years 12 months ago
Computational prediction of type III secreted proteins from gram-negative bacteria
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...