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ISBRA
2007
Springer
15 years 6 months ago
Delta: A Toolset for the Structural Analysis of Biological Sequences on a 3D Triangular Lattice
Abstract. The lattice approach to biological structural analysis was made popular by the HP model for protein folding, but had not been used previously for RNA secondary structure ...
Minghui Jiang, Martin Mayne, Joel Gillespie
BMCBI
2007
144views more  BMCBI 2007»
14 years 12 months ago
Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study an
Background: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. ...
Dennis R. Livesay, Patrick D. Kidd, Sepehr Eskanda...
GCB
2007
Springer
161views Biometrics» more  GCB 2007»
15 years 6 months ago
High-Precision Function Prediction using Conserved Interactions
: The recent availability of large data sets of protein- protein-interactions (PPIs) from various species offers new opportunities for functional genomics and proteomics. We descri...
Samira Jaeger, Ulf Leser
BMCBI
2007
93views more  BMCBI 2007»
14 years 12 months ago
SVM-Fold: a tool for discriminative multi-class protein fold and superfamily recognition
Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...
Iain Melvin, Eugene Ie, Rui Kuang, Jason Weston, W...
92
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CIBCB
2005
IEEE
15 years 5 months ago
The Homology Kernel: A Biologically Motivated Sequence Embedding into Euclidean Space
— Part of the challenge of modeling protein sequences is their discrete nature. Many of the most powerful statistical and learning techniques are applicable to points in a Euclid...
Eleazar Eskin, Sagi Snir