590 search results - page 69 / 118 » Agent-based protein structure prediction |
BMCBI
2008
15 years 13 min ago
2008
Background: The principles of protein folding and evolution pose problems of very high inherent complexity. Often these problems are tackled using simplified protein models, e.g. ...
BMCBI
2008
15 years 54 min ago
2008
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
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JCB
2000
14 years 11 months ago
2000
A previously developed algorithmic method for identifying a geometric invariant of protein structures, termed geometrical core, is extended to the and 1 domains of immunoglobulin ...
BIOINFORMATICS
2010
15 years 8 hour ago
2010
Motivation: To test whether protein folding constraints and secondary structure sequence preferences significantly reduce the space of amino acid words in proteins, we compared th...
BMCBI
2008
15 years 11 min ago
2008
Background: Post-translational modifications have a substantial influence on the structure and functions of protein. Post-translational phosphorylation is one of the most common m...