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» Agent-based protein structure prediction
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BMCBI
2006
85views more  BMCBI 2006»
14 years 12 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen
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NIPS
2004
15 years 1 months ago
Large-Scale Prediction of Disulphide Bond Connectivity
The formation of disulphide bridges among cysteines is an important feature of protein structures. Here we develop new methods for the prediction of disulphide bond connectivity. ...
Pierre Baldi, Jianlin Cheng, Alessandro Vullo
BMCBI
2010
175views more  BMCBI 2010»
15 years 7 hour ago
Calibur: a tool for clustering large numbers of protein decoys
Background: Ab initio protein structure prediction methods generate numerous structural candidates, which are referred to as decoys. The decoy with the most number of neighbors of...
Shuai Cheng Li, Yen Kaow Ng
BMCBI
2006
160views more  BMCBI 2006»
14 years 12 months ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...
JCC
2011
109views more  JCC 2011»
14 years 2 months ago
VoteDock: Consensus docking method for prediction of protein-ligand interactions
: Molecular recognition plays a fundamental role in all biological processes, and that is why great efforts have been made to understand and predict protein–ligand interactions. ...
Dariusz Plewczynski, Michal Lazniewski, Marcin von...