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» Agent-based protein structure prediction
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RECOMB
2009
Springer
16 years 15 days ago
Simultaneous Alignment and Folding of Protein Sequences
Abstract. Accurate comparative analysis tools for low-homology proteins remains a difficult challenge in computational biology, especially sequence alignment and consensus folding ...
Bonnie Berger, Charles W. O'Donnell, Jér&oc...
PAKDD
2009
ACM
233views Data Mining» more  PAKDD 2009»
15 years 4 months ago
A Kernel Framework for Protein Residue Annotation
Abstract. Over the last decade several prediction methods have been developed for determining structural and functional properties of individual protein residues using sequence and...
Huzefa Rangwala, Christopher Kauffman, George Kary...
BIOINFORMATICS
2011
14 years 3 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
ICML
2009
IEEE
16 years 21 days ago
A Bayesian approach to protein model quality assessment
Given multiple possible models b1, b2, . . . bn for a protein structure, a common sub-task in in-silico Protein Structure Prediction is ranking these models according to their qua...
Hetunandan Kamisetty, Christopher James Langmead
BMCBI
2005
198views more  BMCBI 2005»
14 years 11 months ago
Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....