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» Agent-based protein structure prediction
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BMCBI
2011
14 years 3 months ago
Determinants of Antigenicity and Specificity in immune response for Protein Sequences
Background: Target specific antibodies are pivotal for the design of vaccines, immunodiagnostic tests, studies on proteomics for cancer biomarker discovery, identification of prot...
Yulong Wang, Wenjun Wu, Nicolas N. Negre, Kevin P....
BMCBI
2010
159views more  BMCBI 2010»
15 years 9 hour ago
Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
Alvaro J. González, Li Liao
BMCBI
2006
107views more  BMCBI 2006»
14 years 12 months ago
A reinforced merging methodology for mapping unique peptide motifs in members of protein families
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...
Hao-Teng Chang, Tun-Wen Pai, Tan-Chi Fan, Bo-Han S...
NAR
2006
61views more  NAR 2006»
14 years 12 months ago
MAVL/StickWRLD: analyzing structural constraints using interpositional dependencies in biomolecular sequence alignments
The increasing availability of structurally aligned protein families has made it possible to use statistical methods to discover regions of interpositional dependenciesof residue ...
Hatice Gulcin Ozer, William C. Ray
CSB
2005
IEEE
129views Bioinformatics» more  CSB 2005»
15 years 5 months ago
Rule Clustering and Super-rule Generation for Transmembrane Segments Prediction
The explanation of a decision is important for the acceptance of machine learning technology in bioinformatics applications such as protein structure prediction. In past research,...
Jieyue He, Bernard Chen, Hae-Jin Hu, Robert W. Har...