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BMCBI
2010
179views more  BMCBI 2010»
15 years 23 hour ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
BMCBI
2008
160views more  BMCBI 2008»
15 years 19 hour ago
Predicting cancer involvement of genes from heterogeneous data
Background: Systematic approaches for identifying proteins involved in different types of cancer are needed. Experimental techniques such as microarrays are being used to characte...
Ramon Aragues, Chris Sander, Baldo Oliva
JCB
2007
144views more  JCB 2007»
14 years 11 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
BMCBI
2011
14 years 3 months ago
GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
Catherine L. Worth, Annika Kreuchwig, Gunnar Klein...
WSC
2008
15 years 2 months ago
Modeling of air traffic arrival operations through agent-based simulation
This paper reports on the development and validation of an agent based simulation model of air traffic control arrival operations. The simulation model includes modeling of both t...
Sanjiv Shresta, Ralf H. Mayer