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» Agent-oriented modeling of the dynamics of biological organi...
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ISMB
1997
14 years 10 months ago
Standardized Representations of the Literature: Combining Diverse Sources of Ribosomal Data
We are building a knowledge base (KB) of published structural data on the 30s ribosomal subunit in prokaryotes. Our KB is distinguished by a standardized representation of biologi...
Russ B. Altman, Neil F. Abernethy, Richard O. Chen
GECCO
2004
Springer
15 years 2 months ago
Evolved Motor Primitives and Sequences in a Hierarchical Recurrent Neural Network
This study describes how complex goal-directed behavior can evolve in a hierarchically organized recurrent neural network controlling a simulated Khepera robot. Different types of ...
Rainer W. Paine, Jun Tani
BMCBI
2010
150views more  BMCBI 2010»
14 years 9 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
BMCBI
2007
164views more  BMCBI 2007»
14 years 9 months ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...
EVOW
2007
Springer
15 years 3 months ago
Modeling the Shoot Apical Meristem in A. thaliana : Parameter Estimation for Spatial Pattern Formation
Understanding the self-regulatory mechanisms controlling the spatial and temporal structure of multicellular organisms represents one of the major challenges in molecular biology. ...
Tim Hohm, Eckart Zitzler