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126
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BMCBI
2006
108views more  BMCBI 2006»
15 years 2 months ago
Gene function classification using Bayesian models with hierarchy-based priors
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
Babak Shahbaba, Radford M. Neal
112
Voted
BMCBI
2006
144views more  BMCBI 2006»
15 years 2 months ago
methBLAST and methPrimerDB: web-tools for PCR based methylation analysis
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
Filip Pattyn, Jasmien Hoebeeck, Piet Robbrecht, Ev...
BMCBI
2006
129views more  BMCBI 2006»
15 years 2 months ago
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...
BMCBI
2006
135views more  BMCBI 2006»
15 years 2 months ago
iHAP - integrated haplotype analysis pipeline for characterizing the haplotype structure of genes
Background: The advent of genotype data from large-scale efforts that catalog the genetic variants of different populations have given rise to new avenues for multifactorial disea...
Chun Meng Song, Boon Huat Yeo, Erwin Tantoso, Yuch...
CGF
2006
191views more  CGF 2006»
15 years 2 months ago
A Robust Two-Step Procedure for Quad-Dominant Remeshing
We propose a new technique for quad-dominant remeshing which separates the local regularity requirements from the global alignment requirements by working in two steps. In the fir...
Martin Marinov, Leif Kobbelt
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