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» Algorithmic Folding Complexity
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216
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BMCBI
2007
166views more  BMCBI 2007»
15 years 7 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
217
Voted
BMCBI
2008
148views more  BMCBI 2008»
15 years 7 months ago
Critical assessment of alignment procedures for LC-MS proteomics and metabolomics measurements
Background: Liquid chromatography coupled to mass spectrometry (LC-MS) has become a prominent tool for the analysis of complex proteomics and metabolomics samples. In many applica...
Eva Lange, Ralf Tautenhahn, Steffen Neumann, Cleme...
DC
2008
15 years 7 months ago
On implementing omega in systems with weak reliability and synchrony assumptions
We study the feasibility and cost of implementing --a fundamental failure detector at the core of many algorithms--in systems with weak reliability and synchrony assumptions. Intui...
Marcos Kawazoe Aguilera, Carole Delporte-Gallet, H...
BMCBI
2006
138views more  BMCBI 2006»
15 years 7 months ago
Approximation properties of haplotype tagging
Background: Single nucleotide polymorphisms (SNPs) are locations at which the genomic sequences of population members differ. Since these differences are known to follow patterns,...
Staal A. Vinterbo, Stephan Dreiseitl, Lucila Ohno-...
COMGEO
2006
ACM
15 years 7 months ago
Computing homotopic shortest paths efficiently
Geometric shortest paths are a major topic in computational geometry; see the survey paper by Mitchell [12]. A shortest path between two points in a simple polygon can be found in...
Alon Efrat, Stephen G. Kobourov, Anna Lubiw
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