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BMCBI
2010
126views more  BMCBI 2010»
15 years 6 months ago
Cgaln: fast and space-efficient whole-genome alignment
Background: Whole-genome sequence alignment is an essential process for extracting valuable information about the functions, evolution, and peculiarities of genomes under investig...
Ryuichiro Nakato, Osamu Gotoh
BMCBI
2010
105views more  BMCBI 2010»
15 years 6 months ago
Subdivision of the MDR superfamily of medium-chain dehydrogenases/reductases through iterative hidden Markov model refinement
Background: The Medium-chain Dehydrogenases/Reductases (MDR) form a protein superfamily whose size and complexity defeats traditional means of subclassification; it currently has ...
Joel Hedlund, Hans Jörnvall, Bengt Persson
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BMCBI
2007
104views more  BMCBI 2007»
15 years 6 months ago
Joint mapping of genes and conditions via multidimensional unfolding analysis
Background: Microarray compendia profile the expression of genes in a number of experimental conditions. Such data compendia are useful not only to group genes and conditions base...
Katrijn Van Deun, Kathleen Marchal, Willem J. Heis...
BMCBI
2008
140views more  BMCBI 2008»
15 years 6 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh
BMCBI
2007
108views more  BMCBI 2007»
15 years 6 months ago
Computer-aided identification of polymorphism sets diagnostic for groups of bacterial and viral genetic variants
Background: Single nucleotide polymorphisms (SNPs) and genes that exhibit presence/absence variation have provided informative marker sets for bacterial and viral genotyping. Iden...
Erin P. Price, John Inman-Bamber, Venugopal Thiruv...
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