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BMCBI
2010
89views more  BMCBI 2010»
15 years 6 months ago
Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
High-Seng Chai, Terry M. Therneau, Kent R. Bailey,...
BMCBI
2010
115views more  BMCBI 2010»
15 years 6 months ago
Integration of multiple data sources to prioritize candidate genes using discounted rating system
Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their simil...
Yongjin Li, Jagdish Chandra Patra
BMCBI
2010
103views more  BMCBI 2010»
15 years 6 months ago
PostMod: sequence based prediction of kinase-specific phosphorylation sites with indirect relationship
Background: Post-translational modifications (PTMs) have a key role in regulating cell functions. Consequently, identification of PTM sites has a significant impact on understandi...
Inkyung Jung, Akihisa Matsuyama, Minoru Yoshida, D...
BMCBI
2010
160views more  BMCBI 2010»
15 years 6 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BMCBI
2010
118views more  BMCBI 2010»
15 years 6 months ago
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...
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