DNA copy number variants (CNV) are gains and losses of segments of chromosomes, and comprise an important class of genetic variation. Recently, various microarray hybridization ba...
Background: Comorbidity of Major Depressive Disorder (depression) and Alcohol Use Disorders (AUD) is well documented. Depression, AUD, and the comorbidity of depression with AUD s...
Richard C. McEachin, Benjamin J. Keller, Erika F. ...
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Lukas A. Mueller, Adri A. Mills, Beth Skwarecki, R...
Background: Typically, pooling of mRNA samples in microarray experiments implies mixing mRNA from several biological-replicate samples before hybridization onto a microarray chip....
Raghunandan M. Kainkaryam, Angela Bruex, Anna C. G...
Background: Cluster analysis is an important technique for the exploratory analysis of biological data. Such data is often high-dimensional, inherently noisy and contains outliers...
Benjamin Georgi, Ivan Gesteira Costa, Alexander Sc...